Tramadol Information
(Tramadol the most recommend pain relief drug by doctors.)

If you need effective pain relief, please take a few minutes and review the following Tramadol information.

Tramadol has quickly surpassed all other pain relief drugs as the most prescribed pain relief drug by doctors throughout Europe.  Why, because so many doctors have found that Tramadol is a both safe and effective pain relief drug. Tramadol affects chemicals and receptors in the brain that are associated with pain. This association stops the way you perceive pain allowing you to be pain free.

Tramadol, while not technically a narcotic pain reliever, Tramadol does carry many of the same physical responses as narcotic pain relievers. Therefore, Tramadol relieves pain very similar to the narcotic pain relievers, however, Tramadol does not have the potential for addiction as the narcotic drugs.

Tramadol relieves back pain, joint pain, foot pain, knee pain,  arthritis pain, acute or chronic pain, etc.  If you suffer from acute or chronic pain you need Tramadol pain relief medication. Tramadol is a synthetic analogue of codeine that binds to mu opiate receptors and inhibits norepinephrine and serotonin reuptake to stop pain. Tramadol is rapidly absorbed after an oral dose pain relief usually begins within 20 minutes and starts to peak in two hours.

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The chemical name for Tramadol is (±)cis-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl cyclohexanol hydrochloride. Tramadol is a synthetic agent, as a 4-phenyl-piperidine analogue of codeine, and appears to have actions on the GABAergic, noradrenergic and serotonergic systems which are responsible for blocking your sensations to pain. Tramadol was developed by the German pharmaceutical company Grünenthal GmbH.

Additional Tramadol Information

The following Tramadol information has been compiled from a variety of resources in order to give you an accurate summary of how Tramadol effectively relieves pain:

How is Tramadol supplied?

Tramadol is available in both 50mg and 100mg doses.

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What is the recommended dose of Tramadol?

Tramadol should be taken every 4-6 hours as needed for pain relief. Tramadol may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Tramadol exactly as directed.

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What precautions should be taken when using Tramadol?

Prior to taking Tramadol review the following precautions:
 

• Allergies -Tell your doctor if you have ever had any unusual or allergic reaction to Tramadol or codeine or other narcotic analgesics. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
   
• Pregnancy - Tramadol has not been reported to cause birth defects. However, pregnant individuals should not take Tramadol secondary to the potential to harm the fetus.
   
• Breast-feeding - Tramadol passes into breast milk and may cause unwanted effects in nursing babies. Mothers should stop taking Tramadol while breast-feeding.
   
• Medical Conditions - inform your physician if you have or have ever had kidney or liver disease, a history of seizures, or a history of alcohol or drug abuse, Abdominal or stomach conditions (Tramadol may hide signs of these medical conditions), head injury, etc.. If you are having surgery, including dental surgery, tell your physician or dentist that you are taking Tramadol.
   
• Children -There is no specific information concerning the relationship of age to the effects of Tramadol in patients less than 16 years of age.
   
• Older adults - Studies in older adults show that Tramadol has an increased half life (stays in the body a little longer than it does in younger adults).
   
• Contraindications - Inform your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other pain relievers; or other medications i.e., carbamazepine (Tegretol); MAO inhibitors [phenelzine (Nardil) or tranylcypromine (Parnate)]; medications for depression; quinidine; sleeping pills; tranquilizers; and vitamins (see below).
   

Remember, Tramadol may make you drowsy, do not drive a car or operate machinery while taking Tramadol. Remember, Alcohol may add to the drowsiness caused by Tramadol.

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Are there any drug interactions associated with the use of Tramadol?

Certain medicines should not be used together in these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking Tramadol. Inform your doctor of all prescription and nonprescription medications you may use, especially the following:

Carbamazepine (e.g., Tegretol) - may decrease the effects of Tramadol by decreasing the amount of medicine in the body.

Central nervous system (CNS) Anti-Depressants - (e.g., SSRI-types such as fluoxetine or fluvoxamine) using these medicines with Tramadol may increase the chance of serious side effects or increase the risk of convulsions (seizures).

Monoamine Oxidase (MAO) Inhibitors - (furazolidone [e.g., Furoxone], isocarboxazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegiline [e.g., Eldepryl], tranylcypromine [e.g., Parnate])—The chance of convulsions (seizures) may be increased.

Neuroleptics - Chlorpromazine, Triflupromazine, Mesoridazine, Thioridazine, Acetophenazine, Fluphenazine Perphenazine, Prochlorperazine, Trifluoroperazine, Chlorprothixene, Thiothixine, Haloperidol, Loxapine, Molindone, Clozapine, Risperidone, Olanzapine, Quetiapine.

Additional medications - carbamazepine, narcotic pain relievers (e.g., codeine), drugs used to aid sleep, antidepressants psychiatric medicine (e.g., nefazodone), "triptan"-type drugs, anti-anxiety drugs (e.g., diazepam), sibutramine, Digoxin, Warfarin, Coumadin. Also, report use of certain antihistamines (e.g., diphenhydramine) which are also present in many cough-and-cold products. Do not start or stop any medicine without doctor or pharmacist approval.

Please note: The above list is for illustrative purposes and is not all inclusive.

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What if I miss a dose of Tramadol?

Take the missed Tramadol dose as soon as you remember. However, if it is almost time for the next Tramadol dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose of Tramadol to make up for a missed dose of Tramadol.

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